Part 2 of the lecture about Cryo Immune Therapy given by Dr. Israel Barken from the Prostate Research and Education Foundation. Dr. Barken describes Cryo immunotherapy. The reasons why there are no consistent immune response after cryoablation are discussed. Suggestions for further research to enhance the cryoablation immune activation are brought up, based on pre clinical research on the subject. This is the second lecture to be followed up by further evidence of the cryo immunology phenomena.