Alpharadin- Experimental Treatment of Prostate Cancer Metastatic Disease in the Bones

Results of a Phase III trial with Alpharadin (radium 223-chloride) were presented at the European Cancer Organization and Congress of the European Society for Medical Oncology (ECCO-ESMO) conference in Stockholm this year.  Treatment with Alpharadin was associated with a 30% reduction of dying during follow up.  The patients with advanced  metastatic disease in the bone increased average survival (median) from 11.2 months to 14 months.   The trial ended prematurely because of the good results.

Chris Parker, M.D. of the Royal Marsden Hospital in London was interviewed by  Pieter Droppert from Biotech Strategy Blog.

The source of this video is from Pieter Droppert blog   – The Biotech Strategy Blog.     C:\Users\barken\Documents\Ask Dr Barken\jpeg\Peter_Picture.png

This entry was posted in Metastatic Disease, Metastatic Prostate Cancer Disease, Radiation treatment, Treatments for Prostate Cancer and tagged . Bookmark the permalink.

2 Responses to Alpharadin- Experimental Treatment of Prostate Cancer Metastatic Disease in the Bones

  1. I’m stage 4 metastatic bone disease from prostate cancer who has been certified for hospice. Yet when I try to get into clinical trials, I’m told I have to castrate myself first, either chemically or physically. It doesn’t make sense.
    Sterling Greenwood/Aspen

    First, you can ask your oncologist to request any drug on compassionate use. I have done it with the Drug Noscapine, by writing to NCI and got permission to use on a few patients.
    Second, you can ask your oncologist to get in touch with the company and check if there is a possibility to get the drug as a compassionate use.
    Third, there are still a number of treatments which you would qualify , since they can be given for palliation even in the Hospice setting. Infusions of Stillbesterol, Monthly injections of Lanreotide. These are approved drugs which your doctor could try and give you even in your situation.
    Wishing you the best.
    Coach Barken

    • First, you don’t have to join a study to get the drug. You can ask your oncologist to request any drug for you on a compassionate use basis. I have done this for patients with the drug Noscapine, for example, by writing to the NCI and getting permission to use it.
      Or, you can ask your oncologist to get in touch with the drug company that manufactures the drug being used in a clinical trial and check if there is a possibility of getting the drug on a compassionate use basis.

      Please be aware that there are still a number of treatments for which you would qualify, since they can be given for palliation even in the Hospice setting. These include infusions of Stillbesterol and monthly injections of Lanreotide. These are approved drugs which your doctor could try and give you even in your situation. Talk to him.

      Wishing you the best,

      Coach Barken